What is hydroboration oxidation alkyne?

Hydroboration-oxidation of alkynes is a chemical reaction that involves the addition of borane (BH3) and hydrogen peroxide (H2O2) to an alkyne. The reaction proceeds through the formation and subsequent hydroboration of a vinylborane intermediate, followed by oxidation of the boron-containing intermediate to yield an alkene.

The major advantage of hydroboration-oxidation of alkynes over other methods of alkene synthesis is that it is stereospecific and produces cis-alkenes exclusively. Additionally, the reaction is very selective, reacting only with terminal alkynes to yield the desired products.

Hydroboration-oxidation of alkynes finds broad applications in organic chemistry, particularly in the synthesis of complex molecules such as natural products, pharmaceuticals, and polymers. It is also a useful tool in organic synthesis as it offers a mild and efficient method for the preparation of alkenes with high stereoselectivity.